The E3 ubiquitin ligase NEDD4-1 protects against acetaminophen-induced liver injury by targeting VDAC1 for degradation

Acetaminophen (APAP) overdose is a major cause of liver injury. Neural precursor cell expressed developmentally downregulated 4–1 (NEDD4-1) is an E3 ubiquitin ligase that has been implicated in the pathogenesis of numerous liver diseases; however, its role in APAP-induced liver injury (AILI) is uncl...

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Detalles Bibliográficos
Autores principales: Zhu, Yiwei, Lei, Lin, Wang, Xinghui, Chen, Linfang, Li, Wei, Li, Jinxia, Zhao, Chenchen, Du, Xiliang, Song, Yuxiang, Gao, Wenwen, Liu, Guowen, Li, Xinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150139/
https://www.ncbi.nlm.nih.gov/pubmed/37139424
http://dx.doi.org/10.1016/j.apsb.2023.01.019

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