On-demand integrated nano-engager converting cold tumors to hot via increased DNA damage and dual immune checkpoint inhibition

Cancer immunotherapy has become a promising strategy. However, the effectiveness of immunotherapy is restricted in “cold tumors” characterized with insufficient T cells intratumoral infiltration and failed T cells priming. Herein, an on-demand integrated nano-engager (JOT-Lip) was developed to conve...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xiaoqing, Liang, Shuang, Sang, Xiao, Chang, Lili, Fu, Shunli, Yang, Han, Yang, Huizhen, Liu, Yongjun, Zhang, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150160/
https://www.ncbi.nlm.nih.gov/pubmed/37139406
http://dx.doi.org/10.1016/j.apsb.2022.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150160/
https://www.ncbi.nlm.nih.gov/pubmed/37139406
http://dx.doi.org/10.1016/j.apsb.2022.09.004

Ejemplares similares