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On-demand integrated nano-engager converting cold tumors to hot via increased DNA damage and dual immune checkpoint inhibition
Cancer immunotherapy has become a promising strategy. However, the effectiveness of immunotherapy is restricted in “cold tumors” characterized with insufficient T cells intratumoral infiltration and failed T cells priming. Herein, an on-demand integrated nano-engager (JOT-Lip) was developed to conve...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150160/ https://www.ncbi.nlm.nih.gov/pubmed/37139406 http://dx.doi.org/10.1016/j.apsb.2022.09.004 |