Cardiac deficiency of P21-activated kinase 1 promotes atrial arrhythmogenesis in mice following adrenergic challenge

P21-activated kinase 1 (Pak1) signalling plays a vital and overall protective role in the heart. However, the phenotypes of Pak1 deficiency in the cardiac atria have not been well explored. In this study, Pak1 cardiac-conditional knock-out (cKO) mice were studied under baseline and adrenergic challe...

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Detalles Bibliográficos
Autores principales: Jung, Eunjeong, Capel, Rebecca, Jiang, Congshan, Venturi, Elisa, Neagu, Georgiana, Pearcey, Sarah, Zhou, Yafei, Zhang, Yanmin, Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Part V: Cardiac Remodeling and Excitable Properties
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150202/
https://www.ncbi.nlm.nih.gov/pubmed/37122217
http://dx.doi.org/10.1098/rstb.2022.0168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150202/
https://www.ncbi.nlm.nih.gov/pubmed/37122217
http://dx.doi.org/10.1098/rstb.2022.0168

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