Generation of cardiomyocytes from human-induced pluripotent stem cells resembling atrial cells with ability to respond to adrenoceptor agonists

Atrial fibrillation (AF) is the most common chronic arrhythmia presenting a heavy disease burden. We report a new approach for generating cardiomyocytes (CMs) resembling atrial cells from human-induced pluripotent stem cells (hiPSCs) using a combination of Gremlin 2 and retinoic acid treatment. More...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahmad, Faizzan S., Jin, Yongcheng, Grassam-Rowe, Alexander, Zhou, Yafei, Yuan, Meng, Fan, Xuehui, Zhou, Rui, Mu-u-min, Razik, O'Shea, Christopher, Ibrahim, Ayman M., Hyder, Wajiha, Aguib, Yasmine, Yacoub, Magdi, Pavlovic, Davor, Zhang, Yanmin, Tan, Xiaoqiu, Lei, Ming, Terrar, Derek A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Part IV: Autonomic G-Protein Mediated Modulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150206/
https://www.ncbi.nlm.nih.gov/pubmed/37122218
http://dx.doi.org/10.1098/rstb.2022.0312

Ejemplares similares

Ejemplares similares