BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification

The nuclear deubiquitylase BRCA1-associated protein 1 (BAP1) is frequently inactivated in malignant pleural mesothelioma (MPM) and germline BAP1 mutation predisposes to cancers including MPM. To explore the influence on cell physiology and drug sensitivity, we sequentially edited a predisposition mu...

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Detalles Bibliográficos
Autores principales: Barnett, Sarah E., Kenyani, Jenna, Tripari, Martina, Butt, Zohra, Grosman, Rudi, Querques, Francesca, Shaw, Liam, Silva, Luisa C., Goate, Zoe, Marciniak, Stefan J., Rassl, Doris M., Jackson, Richard, Lian, Lu-Yun, Szlosarek, Peter W., Sacco, Joseph J., Coulson, Judy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Cancer Genes and Networks
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150242/
https://www.ncbi.nlm.nih.gov/pubmed/36669126
http://dx.doi.org/10.1158/1541-7786.MCR-22-0635

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