N′-Phenylacetohydrazide Derivatives as Potent Ebola Virus Entry Inhibitors with an Improved Pharmacokinetic Profile

[Image: see text] Ebola virus (EBOV) is a single-strand RNA virus belonging to the Filoviridae family, which has been associated to most Ebola virus disease outbreaks to date, including the West African and the North Kivu epidemics between 2013 and 2022. This unprecedented health emergency prompted...

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Detalles Bibliográficos
Autores principales: Garcia-Rubia, Alfonso, Lasala, Fátima, Ginex, Tiziana, Morales-Tenorio, Marcos, Olal, Catherine, Heung, Michelle, Oquist, Paola, Galindo, Inmaculada, Cuesta-Geijo, Miguel Ángel, Casasnovas, José M., Campillo, Nuria E., Canales, Ángeles, Alonso, Covadonga, Martínez, Ana, Muñoz-Fontela, César, Delgado, Rafael, Gil, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150359/
https://www.ncbi.nlm.nih.gov/pubmed/37021830
http://dx.doi.org/10.1021/acs.jmedchem.2c01785

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