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Macrocycles in Drug Discovery—Learning from the Past for the Future
[Image: see text] We have analyzed FDA-approved macrocyclic drugs, clinical candidates, and the recent literature to understand how macrocycles are used in drug discovery. Current drugs are mainly used in infectious disease and oncology, while oncology is the major indication for the clinical candid...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150360/ https://www.ncbi.nlm.nih.gov/pubmed/37017513 http://dx.doi.org/10.1021/acs.jmedchem.3c00134 |