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Macrocycles in Drug Discovery—Learning from the Past for the Future

[Image: see text] We have analyzed FDA-approved macrocyclic drugs, clinical candidates, and the recent literature to understand how macrocycles are used in drug discovery. Current drugs are mainly used in infectious disease and oncology, while oncology is the major indication for the clinical candid...

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Detalles Bibliográficos
Autores principales:	Garcia Jimenez, Diego, Poongavanam, Vasanthanathan, Kihlberg, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150360/ https://www.ncbi.nlm.nih.gov/pubmed/37017513 http://dx.doi.org/10.1021/acs.jmedchem.3c00134

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