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Catalytically Active Snake Venom PLA(2) Enzymes: An Overview of Its Elusive Mechanisms of Reaction: Miniperspective

[Image: see text] Snake venom-secreted phospholipase A(2) (svPLA(2)) enzymes, both catalytically active and inactive, are a central component in envenoming. These are responsible for disrupting the cell membrane’s integrity, inducing a wide range of pharmacological effects, such as the necrosis of t...

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Detalles Bibliográficos
Autores principales: Castro-Amorim, Juliana, Novo de Oliveira, Ana, Da Silva, Saulo Luís, Soares, Andreimar M., Mukherjee, Ashis K., Ramos, Maria João, Fernandes, Pedro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150362/
https://www.ncbi.nlm.nih.gov/pubmed/37018514
http://dx.doi.org/10.1021/acs.jmedchem.3c00097