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Drug interactions between ALK inhibitors and warfarin with concurrent use of bucolome: a case report

BACKGROUND: Alectinib, crizotinib, and ceritinib, are anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs) that exhibit high protein binding, and their metabolism is associated with the cytochrome P450 (CYP) isoenzymes 2C9 or 3A4. The plasma protein binding rate of warfarin, which is use...

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Detalles Bibliográficos
Autores principales:	Kato, Takashi, Kunimoto, Yusuke, Kitagawa, Manabu, Asai, Yuichiro, Kimyo, Tomoko, Nakata, Hiromasa, Takahashi, Mamoru, Chiba, Hirofumi, Takahashi, Hiroki, Miyamoto, Atsushi, Fukudo, Masahide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150460/ https://www.ncbi.nlm.nih.gov/pubmed/37122027 http://dx.doi.org/10.1186/s40780-023-00282-1

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