STING controls opioid-induced itch and chronic itch via spinal tank-binding kinase 1-dependent type I interferon response in mice

BACKGROUND: Patients receiving epidural or intrathecal opioids administration for neuraxial analgesia frequently suffer from an irritating itch. STING (stimulator of interferon genes), an innate immune modulator, is strongly implicated in pain pathogenesis via neuron-immune modulation. Given that pa...

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Detalles Bibliográficos
Autores principales: Li, Nan, Wang, Chunyan, Zhao, Yuying, Wang, Yigang, Gao, Tianyu, Yu, Yonghao, Wang, Guolin, Zhang, Linlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150483/
https://www.ncbi.nlm.nih.gov/pubmed/37122031
http://dx.doi.org/10.1186/s12974-023-02783-0

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