Caloric restriction remodels the hepatic chromatin landscape and bile acid metabolism by modulating the gut microbiota

BACKGROUND: Caloric restriction (CR) has been known to promote health by reprogramming metabolism, yet little is known about how the epigenome and microbiome respond during metabolic adaptation to CR. RESULTS: We investigate chromatin modifications, gene expression, as well as alterations in microbi...

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Detalles Bibliográficos
Autores principales: Fan, Yun, Qian, Hong, Zhang, Meijia, Tao, Chengzhe, Li, Zhi, Yan, Wenkai, Huang, Yuna, Zhang, Yan, Xu, Qiaoqiao, Wang, Xinru, Wade, Paul A., Xia, Yankai, Qin, Yufeng, Lu, Chuncheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150505/
https://www.ncbi.nlm.nih.gov/pubmed/37122023
http://dx.doi.org/10.1186/s13059-023-02938-5

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