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Leading edge competition promotes context-dependent responses to receptor inputs to resolve directional dilemmas in neutrophil migration

Maintaining persistent migration in complex environments is critical for neutrophils to reach infection sites. Neutrophils avoid getting trapped, even when obstacles split their front into multiple leading edges. How they re-establish polarity to move productively while incorporating receptor inputs...

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Detalles Bibliográficos
Autores principales: Hadjitheodorou, Amalia, Bell, George R. R., Ellett, Felix, Irimia, Daniel, Tibshirani, Robert, Collins, Sean R., Theriot, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150694/
https://www.ncbi.nlm.nih.gov/pubmed/36827986
http://dx.doi.org/10.1016/j.cels.2023.02.001

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