Development of Diphenyl carbonate-Crosslinked Cyclodextrin Based Nanosponges for Oral Delivery of Baricitinib: Formulation, Characterization and Pharmacokinetic Studies

BACKGROUND: The aim of the present investigation is to prepare baricitinib (BAR)-loaded diphenyl carbonate (DPC) β-cyclodextrin (βCD) based nanosponges (NSs) to improve the oral bioavailability. METHODS: BAR-loaded DPC-crosslinked βCD NSs (B-DCNs) were prepared prepared by varying the molar ratio of...

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Detalles Bibliográficos
Autores principales: Aldawsari, Mohammed F, Alhowail, Ahmad H, Anwer, Md Khalid, Ahmed, Mohammed Muqtader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150753/
https://www.ncbi.nlm.nih.gov/pubmed/37139486
http://dx.doi.org/10.2147/IJN.S405534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150753/
https://www.ncbi.nlm.nih.gov/pubmed/37139486
http://dx.doi.org/10.2147/IJN.S405534

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