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Carcinosarcoma: A Rare and Aggressive Breast Tumor in a Young Lady

Carcinosarcoma of the breast is a subtype of metaplastic breast carcinoma characterized by differentiation of the neoplastic epithelium toward mesenchymal-looking elements. It is a highly aggressive rare subtype of invasive breast neoplasm that exhibits a distinct histologic entity. Only a limited n...

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Detalles Bibliográficos
Autores principales: Leng, Poh Nuan, Wan Zain, Wan Zainira, Mohammad Azmi, Mohd Azem Fathi, Yahya, Maya Mazuwin, Azis, Khairul Anuar, Mat Johar, Siti Fatimah Noor, Wan Sulaiman, Wan Azman, Balingi, Dumin, Tuan Sharif, Sharifah Emilia, Wan Abdul Rahman, Wan Faiziah, Chiew Chea, Lau, Haron, Juhara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150779/
https://www.ncbi.nlm.nih.gov/pubmed/37139022
http://dx.doi.org/10.7759/cureus.37003
Descripción
Sumario:Carcinosarcoma of the breast is a subtype of metaplastic breast carcinoma characterized by differentiation of the neoplastic epithelium toward mesenchymal-looking elements. It is a highly aggressive rare subtype of invasive breast neoplasm that exhibits a distinct histologic entity. Only a limited number of reports related to this type of disease have been reported. Here, we present a case of breast carcinosarcoma in a lady in her early 20s, which is relatively young among all cases published. It was challenging to achieve diagnosis preoperatively with histopathological evaluation of the ultrasound-guided tru-cut biopsy sample. With no evidence of distant metastasis clinically and radiologically, a surgical option was opted for. Left mastectomy and left chest wall reconstruction with deep inferior epigastric artery free flap were performed. Post-excision specimen was confirmed to be carcinosarcoma.