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Carcinosarcoma: A Rare and Aggressive Breast Tumor in a Young Lady
Carcinosarcoma of the breast is a subtype of metaplastic breast carcinoma characterized by differentiation of the neoplastic epithelium toward mesenchymal-looking elements. It is a highly aggressive rare subtype of invasive breast neoplasm that exhibits a distinct histologic entity. Only a limited n...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150779/ https://www.ncbi.nlm.nih.gov/pubmed/37139022 http://dx.doi.org/10.7759/cureus.37003 |
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author | Leng, Poh Nuan Wan Zain, Wan Zainira Mohammad Azmi, Mohd Azem Fathi Yahya, Maya Mazuwin Azis, Khairul Anuar Mat Johar, Siti Fatimah Noor Wan Sulaiman, Wan Azman Balingi, Dumin Tuan Sharif, Sharifah Emilia Wan Abdul Rahman, Wan Faiziah Chiew Chea, Lau Haron, Juhara |
author_facet | Leng, Poh Nuan Wan Zain, Wan Zainira Mohammad Azmi, Mohd Azem Fathi Yahya, Maya Mazuwin Azis, Khairul Anuar Mat Johar, Siti Fatimah Noor Wan Sulaiman, Wan Azman Balingi, Dumin Tuan Sharif, Sharifah Emilia Wan Abdul Rahman, Wan Faiziah Chiew Chea, Lau Haron, Juhara |
author_sort | Leng, Poh Nuan |
collection | PubMed |
description | Carcinosarcoma of the breast is a subtype of metaplastic breast carcinoma characterized by differentiation of the neoplastic epithelium toward mesenchymal-looking elements. It is a highly aggressive rare subtype of invasive breast neoplasm that exhibits a distinct histologic entity. Only a limited number of reports related to this type of disease have been reported. Here, we present a case of breast carcinosarcoma in a lady in her early 20s, which is relatively young among all cases published. It was challenging to achieve diagnosis preoperatively with histopathological evaluation of the ultrasound-guided tru-cut biopsy sample. With no evidence of distant metastasis clinically and radiologically, a surgical option was opted for. Left mastectomy and left chest wall reconstruction with deep inferior epigastric artery free flap were performed. Post-excision specimen was confirmed to be carcinosarcoma. |
format | Online Article Text |
id | pubmed-10150779 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-101507792023-05-02 Carcinosarcoma: A Rare and Aggressive Breast Tumor in a Young Lady Leng, Poh Nuan Wan Zain, Wan Zainira Mohammad Azmi, Mohd Azem Fathi Yahya, Maya Mazuwin Azis, Khairul Anuar Mat Johar, Siti Fatimah Noor Wan Sulaiman, Wan Azman Balingi, Dumin Tuan Sharif, Sharifah Emilia Wan Abdul Rahman, Wan Faiziah Chiew Chea, Lau Haron, Juhara Cureus Pathology Carcinosarcoma of the breast is a subtype of metaplastic breast carcinoma characterized by differentiation of the neoplastic epithelium toward mesenchymal-looking elements. It is a highly aggressive rare subtype of invasive breast neoplasm that exhibits a distinct histologic entity. Only a limited number of reports related to this type of disease have been reported. Here, we present a case of breast carcinosarcoma in a lady in her early 20s, which is relatively young among all cases published. It was challenging to achieve diagnosis preoperatively with histopathological evaluation of the ultrasound-guided tru-cut biopsy sample. With no evidence of distant metastasis clinically and radiologically, a surgical option was opted for. Left mastectomy and left chest wall reconstruction with deep inferior epigastric artery free flap were performed. Post-excision specimen was confirmed to be carcinosarcoma. Cureus 2023-04-01 /pmc/articles/PMC10150779/ /pubmed/37139022 http://dx.doi.org/10.7759/cureus.37003 Text en Copyright © 2023, Leng et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Pathology Leng, Poh Nuan Wan Zain, Wan Zainira Mohammad Azmi, Mohd Azem Fathi Yahya, Maya Mazuwin Azis, Khairul Anuar Mat Johar, Siti Fatimah Noor Wan Sulaiman, Wan Azman Balingi, Dumin Tuan Sharif, Sharifah Emilia Wan Abdul Rahman, Wan Faiziah Chiew Chea, Lau Haron, Juhara Carcinosarcoma: A Rare and Aggressive Breast Tumor in a Young Lady |
title | Carcinosarcoma: A Rare and Aggressive Breast Tumor in a Young Lady |
title_full | Carcinosarcoma: A Rare and Aggressive Breast Tumor in a Young Lady |
title_fullStr | Carcinosarcoma: A Rare and Aggressive Breast Tumor in a Young Lady |
title_full_unstemmed | Carcinosarcoma: A Rare and Aggressive Breast Tumor in a Young Lady |
title_short | Carcinosarcoma: A Rare and Aggressive Breast Tumor in a Young Lady |
title_sort | carcinosarcoma: a rare and aggressive breast tumor in a young lady |
topic | Pathology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150779/ https://www.ncbi.nlm.nih.gov/pubmed/37139022 http://dx.doi.org/10.7759/cureus.37003 |
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