Blockade of Annexin A2 Prevents Early Microvasculopathy in Murine Models of Diabetic Retinopathy

PURPOSE: We examined the role of annexin A2 (A2) in the development of diabetic retinal vasculopathy by testing the effect of Anxa2 gene deletion as well as administration of anti-A2 antibodies on pericyte dropout and retinal neovascularization in diabetic Akita mice, and in mice subjected to oxygen...

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Detalles Bibliográficos
Autores principales: Dallacasagrande, Valentina, Liu, Wei, Almeida, Dena, Luo, Min, Hajjar, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150831/
https://www.ncbi.nlm.nih.gov/pubmed/37103008
http://dx.doi.org/10.1167/iovs.64.4.33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150831/
https://www.ncbi.nlm.nih.gov/pubmed/37103008
http://dx.doi.org/10.1167/iovs.64.4.33

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