PHT427 as an effective New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor restored the susceptibility of meropenem against Enterobacteriaceae producing NDM-1

INTRODUCTION: With the increasingly serious problem of bacterial drug resistance caused by NDM-1, it is an important strategy to find effective inhibitors to assist β-lactam antibiotic treatment against NDM-1 resistant bacteria. In this study, PHT427 (4-dodecyl-N-1,3,4-thiadiazol-2-yl-benzenesulfona...

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Detalles Bibliográficos
Autores principales: Li, Xiaohui, Wang, Qian, Zheng, Ji, Guan, Yan, Liu, Chennan, Han, Jiangxue, Liu, Sihan, Liu, Tianjun, Xiao, Chunling, Wang, Xiao, Liu, Yishuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150926/
https://www.ncbi.nlm.nih.gov/pubmed/37138606
http://dx.doi.org/10.3389/fmicb.2023.1168052

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