Rare Presentation of Acute Myeloid Leukemia With TP53 Mutation and Dermatologic Manifestations

Acute myeloid leukemia (AML) is a complex and aggressive malignancy that occurs due to genetic mutations and subsequent stem cell overproduction. We report a case of a patient with AML and a highly fatal, uncommon TP53 mutation who developed dermatologic manifestations. This report serves to highlig...

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Detalles Bibliográficos
Autores principales: Lott, Ronald, Stawitzky, Sara, Stroia, Alexandra, Awad, Angela, Kam, Anthony, Bleicher, Maxim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150939/
https://www.ncbi.nlm.nih.gov/pubmed/37139024
http://dx.doi.org/10.7759/cureus.37012
Descripción
Sumario:Acute myeloid leukemia (AML) is a complex and aggressive malignancy that occurs due to genetic mutations and subsequent stem cell overproduction. We report a case of a patient with AML and a highly fatal, uncommon TP53 mutation who developed dermatologic manifestations. This report serves to highlight the importance of dermatologic findings in underlying leukemia and educate healthcare providers on the diagnosis and treatment of a rare TP53 mutation in AML.

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