A coarse-grained molecular dynamics investigation on spontaneous binding of Aβ(1–40) fibrils with cholesterol-mixed DPPC bilayers

Alzheimer's disease is the most common form of dementia. Its aetiology is characterized by the misfolding and aggregation of amyloid-β (Aβ) peptides into β-sheet-rich Aβ oligomers/fibrils. Although multiple experimental studies have suggested that Aβ oligomers/fibrils interact with the cell mem...

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Detalles Bibliográficos
Autores principales: Agrawal, Nikhil, Skelton, Adam A., Parisini, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151222/
https://www.ncbi.nlm.nih.gov/pubmed/37143763
http://dx.doi.org/10.1016/j.csbj.2023.04.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151222/
https://www.ncbi.nlm.nih.gov/pubmed/37143763
http://dx.doi.org/10.1016/j.csbj.2023.04.013

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