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A coarse-grained molecular dynamics investigation on spontaneous binding of Aβ(1–40) fibrils with cholesterol-mixed DPPC bilayers
Alzheimer's disease is the most common form of dementia. Its aetiology is characterized by the misfolding and aggregation of amyloid-β (Aβ) peptides into β-sheet-rich Aβ oligomers/fibrils. Although multiple experimental studies have suggested that Aβ oligomers/fibrils interact with the cell mem...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151222/ https://www.ncbi.nlm.nih.gov/pubmed/37143763 http://dx.doi.org/10.1016/j.csbj.2023.04.013 |