Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study

This is a multicentre prospective cohort including critically ill children and adolescents, with confirmed critical disease related to SARS-CoV-2, admitted to three tertiary paediatric intensive care units in the Brazilian Amazon, between April 2020 and July 2022. 208 patients were included (median...

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Detalles Bibliográficos
Autores principales: de Farias, Emmerson Carlos Franco, Pavão Júnior, Manoel Jaime Castro, de Sales, Susan C D, do Nascimento, Luciana M P P, de Mello, Mary, Carvalho, Patricia, Terreri, Maria Teresa, Clemente, Gleice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Original Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151234/
https://www.ncbi.nlm.nih.gov/pubmed/37185653
http://dx.doi.org/10.1136/bmjpo-2023-001865
Descripción
Sumario:This is a multicentre prospective cohort including critically ill children and adolescents, with confirmed critical disease related to SARS-CoV-2, admitted to three tertiary paediatric intensive care units in the Brazilian Amazon, between April 2020 and July 2022. 208 patients were included (median age was 3.5 years). The majority had malnutrition (62%) and comorbidities (60.6%). Mechanical ventilation support, cardiogenic shock and acute respiratory distress syndrome occurred in 47%, 30% and 34.1% of patients, respectively. There were 37 (18%) deaths. A poor outcome of severe COVID-19 and multisystem inflammatory syndrome in children was observed in children and adolescents from the Brazilian Amazon.

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