Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study

This is a multicentre prospective cohort including critically ill children and adolescents, with confirmed critical disease related to SARS-CoV-2, admitted to three tertiary paediatric intensive care units in the Brazilian Amazon, between April 2020 and July 2022. 208 patients were included (median...

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Autores principales: de Farias, Emmerson Carlos Franco, Pavão Júnior, Manoel Jaime Castro, de Sales, Susan C D, do Nascimento, Luciana M P P, de Mello, Mary, Carvalho, Patricia, Terreri, Maria Teresa, Clemente, Gleice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Original Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151234/
https://www.ncbi.nlm.nih.gov/pubmed/37185653
http://dx.doi.org/10.1136/bmjpo-2023-001865
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author de Farias, Emmerson Carlos Franco
Pavão Júnior, Manoel Jaime Castro
de Sales, Susan C D
do Nascimento, Luciana M P P
de Mello, Mary
Carvalho, Patricia
Terreri, Maria Teresa
Clemente, Gleice
author_facet de Farias, Emmerson Carlos Franco
Pavão Júnior, Manoel Jaime Castro
de Sales, Susan C D
do Nascimento, Luciana M P P
de Mello, Mary
Carvalho, Patricia
Terreri, Maria Teresa
Clemente, Gleice
author_sort de Farias, Emmerson Carlos Franco
collection PubMed
description This is a multicentre prospective cohort including critically ill children and adolescents, with confirmed critical disease related to SARS-CoV-2, admitted to three tertiary paediatric intensive care units in the Brazilian Amazon, between April 2020 and July 2022. 208 patients were included (median age was 3.5 years). The majority had malnutrition (62%) and comorbidities (60.6%). Mechanical ventilation support, cardiogenic shock and acute respiratory distress syndrome occurred in 47%, 30% and 34.1% of patients, respectively. There were 37 (18%) deaths. A poor outcome of severe COVID-19 and multisystem inflammatory syndrome in children was observed in children and adolescents from the Brazilian Amazon.
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spelling pubmed-101512342023-05-02 Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study de Farias, Emmerson Carlos Franco Pavão Júnior, Manoel Jaime Castro de Sales, Susan C D do Nascimento, Luciana M P P de Mello, Mary Carvalho, Patricia Terreri, Maria Teresa Clemente, Gleice BMJ Paediatr Open Original Research Letter This is a multicentre prospective cohort including critically ill children and adolescents, with confirmed critical disease related to SARS-CoV-2, admitted to three tertiary paediatric intensive care units in the Brazilian Amazon, between April 2020 and July 2022. 208 patients were included (median age was 3.5 years). The majority had malnutrition (62%) and comorbidities (60.6%). Mechanical ventilation support, cardiogenic shock and acute respiratory distress syndrome occurred in 47%, 30% and 34.1% of patients, respectively. There were 37 (18%) deaths. A poor outcome of severe COVID-19 and multisystem inflammatory syndrome in children was observed in children and adolescents from the Brazilian Amazon. BMJ Publishing Group 2023-04-25 /pmc/articles/PMC10151234/ /pubmed/37185653 http://dx.doi.org/10.1136/bmjpo-2023-001865 Text en © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Original Research Letter
de Farias, Emmerson Carlos Franco
Pavão Júnior, Manoel Jaime Castro
de Sales, Susan C D
do Nascimento, Luciana M P P
de Mello, Mary
Carvalho, Patricia
Terreri, Maria Teresa
Clemente, Gleice
Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study
title Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study
title_full Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study
title_fullStr Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study
title_full_unstemmed Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study
title_short Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study
title_sort critical disease related to sars-cov-2 infection in children from the amazon region: an observational study
topic Original Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151234/
https://www.ncbi.nlm.nih.gov/pubmed/37185653
http://dx.doi.org/10.1136/bmjpo-2023-001865
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