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Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina

Adenylyl cyclase 6 (AC6) synthesizes second messenger cAMP in G protein-coupled receptor (GPCR) signaling. In cochlear hair cells, AC6 distribution relies on an adhesion GPCR, ADGRV1, which is associated with Usher syndrome (USH), a condition of combined hearing and vision loss. ADGRV1 is a componen...

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Detalles Bibliográficos
Autores principales:	Mathur, Pranav Dinesh, Zou, Junhuang, Neiswanger, Grace, Zhu, Daniel, Wang, Yong, Almishaal, Ali A., Vashist, Deepti, Hammond, H. Kirk, Park, Albert H., Yang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151359/ https://www.ncbi.nlm.nih.gov/pubmed/37127773 http://dx.doi.org/10.1038/s41598-023-34361-y

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