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Deletion of MEC1 suppresses the replicative senescence of the cdc13-2 mutant in Saccharomyces cerevisiae

In Saccharomyces cerevisiae, telomerase recruitment to telomeres depends on a direct interaction between Cdc13, a protein that binds single-stranded telomeric DNA, and the Est1 subunit of telomerase. The cdc13-2 allele disrupts telomerase association with telomeres, resulting in progressive telomere...

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Detalles Bibliográficos
Autores principales:	Yao, Yue, Fekete-Szücs, Enikő, Rosas Bringas, Fernando R, Chang, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151410/ https://www.ncbi.nlm.nih.gov/pubmed/36947417 http://dx.doi.org/10.1093/g3journal/jkad065

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