Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein

Octopamine is a well-established invertebrate neurotransmitter involved in fight or flight responses. In mammals, its function was replaced by epinephrine. Nevertheless, it is present at trace amounts and can modulate the release of monoamine neurotransmitters by a yet unidentified mechanism. Here,...

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Detalles Bibliográficos
Autores principales: Shum, Andrew, Zaichick, Sofia, McElroy, Gregory S., D’Alessandro, Karis, Alasady, Milad J., Novakovic, Michaela, Peng, Wesley, Grebenik, Ekaterina A., Chung, Daayun, Flanagan, Margaret E., Smith, Roger, Morales, Alejandro, Stumpf, Laetitia, McGrath, Kaitlyn, Krainc, Dimitri, Mendillo, Marc L., Prakriya, Murali, Chandel, Navdeep S., Caraveo, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151466/
https://www.ncbi.nlm.nih.gov/pubmed/37068235
http://dx.doi.org/10.1073/pnas.2217396120

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