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Developmental origin of tendon diversity in Drosophila melanogaster
Myogenesis is a developmental process that is largely conserved in both Drosophila and higher organisms. Consequently, the fruit fly is an excellent in vivo model for identifying the genes and mechanisms involved in muscle development. Moreover, there is growing evidence indicating that specific con...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151533/ https://www.ncbi.nlm.nih.gov/pubmed/37143929 http://dx.doi.org/10.3389/fphys.2023.1176148 |
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author | Moucaud, Blandine Prince, Elodie Jagla, Krzysztof Soler, Cédric |
author_facet | Moucaud, Blandine Prince, Elodie Jagla, Krzysztof Soler, Cédric |
author_sort | Moucaud, Blandine |
collection | PubMed |
description | Myogenesis is a developmental process that is largely conserved in both Drosophila and higher organisms. Consequently, the fruit fly is an excellent in vivo model for identifying the genes and mechanisms involved in muscle development. Moreover, there is growing evidence indicating that specific conserved genes and signaling pathways govern the formation of tissues that connect the muscles to the skeleton. In this review, we present an overview of the different stages of tendon development, from the specification of tendon progenitors to the assembly of a stable myotendinous junction across three different myogenic contexts in Drosophila: larval, flight and leg muscle development. We underline the different aspects of tendon cell specification and differentiation in embryo and during metamorphosis that result into tendon morphological and functional diversity. |
format | Online Article Text |
id | pubmed-10151533 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-101515332023-05-03 Developmental origin of tendon diversity in Drosophila melanogaster Moucaud, Blandine Prince, Elodie Jagla, Krzysztof Soler, Cédric Front Physiol Physiology Myogenesis is a developmental process that is largely conserved in both Drosophila and higher organisms. Consequently, the fruit fly is an excellent in vivo model for identifying the genes and mechanisms involved in muscle development. Moreover, there is growing evidence indicating that specific conserved genes and signaling pathways govern the formation of tissues that connect the muscles to the skeleton. In this review, we present an overview of the different stages of tendon development, from the specification of tendon progenitors to the assembly of a stable myotendinous junction across three different myogenic contexts in Drosophila: larval, flight and leg muscle development. We underline the different aspects of tendon cell specification and differentiation in embryo and during metamorphosis that result into tendon morphological and functional diversity. Frontiers Media S.A. 2023-04-18 /pmc/articles/PMC10151533/ /pubmed/37143929 http://dx.doi.org/10.3389/fphys.2023.1176148 Text en Copyright © 2023 Moucaud, Prince, Jagla and Soler. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Physiology Moucaud, Blandine Prince, Elodie Jagla, Krzysztof Soler, Cédric Developmental origin of tendon diversity in Drosophila melanogaster |
title | Developmental origin of tendon diversity in Drosophila melanogaster
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title_full | Developmental origin of tendon diversity in Drosophila melanogaster
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title_fullStr | Developmental origin of tendon diversity in Drosophila melanogaster
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title_full_unstemmed | Developmental origin of tendon diversity in Drosophila melanogaster
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title_short | Developmental origin of tendon diversity in Drosophila melanogaster
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title_sort | developmental origin of tendon diversity in drosophila melanogaster |
topic | Physiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151533/ https://www.ncbi.nlm.nih.gov/pubmed/37143929 http://dx.doi.org/10.3389/fphys.2023.1176148 |
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