Cargando…

Phospholamban R14del disease: The past, the present and the future

Arrhythmogenic cardiomyopathy affects significant number of patients worldwide and is characterized by life-threatening ventricular arrhythmias and sudden cardiac death. Mutations in multiple genes with diverse functions have been reported to date including phospholamban (PLN), a key regulator of sa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vafiadaki, Elizabeth, Glijnis, Pieter C., Doevendans, Pieter A., Kranias, Evangelia G., Sanoudou, Despina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151546/ https://www.ncbi.nlm.nih.gov/pubmed/37144056 http://dx.doi.org/10.3389/fcvm.2023.1162205

Ejemplares similares

Identification of a Protein Phosphatase-1/Phospholamban Complex That Is Regulated by cAMP-Dependent Phosphorylation
por: Vafiadaki, Elizabeth, et al.
Publicado: (2013)

Impaired Right Ventricular Calcium Cycling Is an Early Risk Factor in R14del-Phospholamban Arrhythmias
por: Haghighi, Kobra, et al.
Publicado: (2021)

Aberrant PLN-R14del Protein Interactions Intensify SERCA2a Inhibition, Driving Impaired Ca(2+) Handling and Arrhythmogenesis
por: Vafiadaki, Elizabeth, et al.
Publicado: (2022)

Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy
por: Kumar, Mohit, et al.
Publicado: (2023)

The Histidine-Rich Calcium Binding Protein in Regulation of Cardiac Rhythmicity
por: Arvanitis, Demetrios A., et al.
Publicado: (2018)

The Cardioprotective PKA-Mediated Hsp20 Phosphorylation Modulates Protein Associations Regulating Cytoskeletal Dynamics
por: Vafiadaki, Elizabeth, et al.
Publicado: (2020)

Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy
por: Karakikes, Ioannis, et al.
Publicado: (2015)

Prevalence and cardiac phenotype of patients with a phospholamban mutation
por: Hof, I. E., et al.
Publicado: (2018)

The role of CaMKII regulation of phospholamban activity in heart disease
por: Mattiazzi, Alicia, et al.
Publicado: (2014)

Clinical magnetocardiography: the unshielded bet—past, present, and future
por: Brisinda, D., et al.
Publicado: (2023)

Evolving cardiovascular genetic counseling needs in the era of precision medicine
por: Morales, Ana, et al.
Publicado: (2023)

Women physicians in cardiovascular magnetic resonance: Past, present, and future
por: Sierra-Galan, Lilia M., et al.
Publicado: (2023)

Therapeutic Targets and Personalized Medicine in Cardiac Disease
por: Vafiadaki, Elizabeth, et al.
Publicado: (2023)

Review: Precision Medicine Approaches for Genetic Cardiomyopathy: Targeting Phospholamban R14del
por: Deiman, Frederik E., et al.
Publicado: (2022)

Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model of phospholamban R14del cardiomyopathy
por: Kamel, S. M., et al.
Publicado: (2021)

Percutaneous Device to Narrow the Coronary Sinus: Shifting Paradigm in the Treatment of Refractory Angina? A Review of the Literature
por: Benedetto, Daniela, et al.
Publicado: (2016)

The Ser96Ala variant in histidine-rich calcium-binding protein is associated with life-threatening ventricular arrhythmias in idiopathic dilated cardiomyopathy
por: Arvanitis, Demetrios A., et al.
Publicado: (2008)

Phospholamban p.Arg14del Cardiomyopathy: A Japanese Case Series
por: Tabata, Tomoka, et al.
Publicado: (2021)

Protein Aggregation Is an Early Manifestation of Phospholamban p.(Arg14del)–Related Cardiomyopathy: Development of PLN-R14del–Related Cardiomyopathy
por: Eijgenraam, Tim R., et al.
Publicado: (2021)

Historical Context of Cardiac Rehabilitation: Learning From the Past to Move to the Future
por: Redfern, Julie, et al.
Publicado: (2022)

NeuroMind: Past, present, and future
por: Kubben, Pieter L.
Publicado: (2017)

The phospholamban p.Arg14del founder mutation in Dutch patients with arrhythmogenic cardiomyopathy
por: van der Heijden, J. F., et al.
Publicado: (2013)

miR-132/212 Impairs Cardiomyocytes Contractility in the Failing Heart by Suppressing SERCA2a
por: Lei, Zhiyong, et al.
Publicado: (2021)

Angiotensin Converting Enzyme Inhibitors (ACEIs) Decrease the Progression of Cardiac Fibrosis in Rheumatic Heart Disease Through the Inhibition of IL-33/sST2
por: Ambari, Ade M., et al.
Publicado: (2020)

A randomized controlled trial of eplerenone in asymptomatic phospholamban p.Arg14del carriers
por: de Brouwer, Remco, et al.
Publicado: (2023)

Generation of two induced pluripotent stem cell lines carrying the phospholamban R14del mutation for modeling ARVD/C
por: Vera, Carlos D., et al.
Publicado: (2022)

Randomised controlled trial into the role of ramipril in fibrosis reduction in rheumatic heart disease: the RamiRHeD trial protocol
por: Ambari, Ade Meidian, et al.
Publicado: (2021)

Past, present and future in low-risk myelodysplastic syndrome
por: Toprak, Selami Kocak
Publicado: (2022)

Cardiomyocyte Specific Deletion of ADAR1 Causes Severe Cardiac Dysfunction and Increased Lethality
por: el Azzouzi, Hamid, et al.
Publicado: (2020)

Recurrent and founder mutations in the Netherlands—Phospholamban p.Arg14del mutation causes arrhythmogenic cardiomyopathy
por: van der Zwaag, P. A., et al.
Publicado: (2013)

Antisense Therapy Attenuates Phospholamban p.(Arg14del) Cardiomyopathy in Mice and Reverses Protein Aggregation
por: Eijgenraam, Tim R., et al.
Publicado: (2022)

Artificial intelligence in cardiology: Hope for the future and power for the present
por: Karatzia, Loucia, et al.
Publicado: (2022)

Societies of Futures Past: Examining the History and Potential of International Society Collaborations in Addressing the Burden of Rheumatic Heart Disease in the Developing World
por: Enumah, Zachary Obinna, et al.
Publicado: (2021)

Should we offer preventive treatment to all carriers of PLN p.(Arg14del) variant?: Con: Do no harm to asymptomatic carriers
por: Doevendans, Pieter A.
Publicado: (2023)

Exploring the research landscape of the past, present, and future of thyroid nodules
por: Chen, Pei, et al.
Publicado: (2023)

Glial responses during epileptogenesis in Mus musculus point to potential therapeutic targets
por: Kalozoumi, Georgia, et al.
Publicado: (2018)

Future Costs in Cost-Effectiveness Analyses: Past, Present, Future
por: de Vries, Linda M., et al.
Publicado: (2018)

3213 Unraveling the role of Phospholamban (PLN) in humans via the characterization of Induced Pluripotent Stem Cell (iPSC) Cardiomyocytes (CM) derived from carriers of a lethal PLN mutation
por: Trivieri, Maria Giovanna, et al.
Publicado: (2019)

Advanced image-supported lead placement in cardiac resynchronisation therapy: protocol for the multicentre, randomised controlled ADVISE trial and early economic evaluation
por: Wouters, Philippe C, et al.
Publicado: (2021)

Optimal echocardiographic assessment of myocardial dysfunction for arrhythmic risk stratification in phospholamban mutation carriers( )
por: Taha, Karim, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_918g97r8btl9cil2bu4bsc09n0