Cargando…

12/15-lipoxygenase activity promotes efficient inflammation resolution in a murine model of Lyme arthritis

Infection of C3H/HeJ (C3H) mice with Borrelia burgdorferi results in the development of a robust inflammatory arthritis that peaks around 3-4 weeks post-infection and then spontaneously resolves over the next few weeks. Mice lacking cyclooxygenase (COX)-2 or 5-lipoxygenase (5-LO) activity develop ar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jackson, Christa D., Hilliard, Kinsey A., Brown, Charles R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151577/ https://www.ncbi.nlm.nih.gov/pubmed/37143678 http://dx.doi.org/10.3389/fimmu.2023.1144172

Ejemplares similares

T Cells Exacerbate Lyme Borreliosis in TLR2-Deficient Mice
por: Lasky, Carrie E., et al.
Publicado: (2016)

12/15-Lipoxygenase Regulates IL-33-Induced Eosinophilic Airway Inflammation in Mice
por: Miyata, Jun, et al.
Publicado: (2021)

Cardiac 12/15 lipoxygenase–induced inflammation is involved in heart failure
por: Kayama, Yosuke, et al.
Publicado: (2009)

Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids
por: Gheorghe, Karina Roxana, et al.
Publicado: (2009)

Regulation of Tissue Inflammation by 12-Lipoxygenases
por: Kulkarni, Abhishek, et al.
Publicado: (2021)

Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution
por: Rao, Zhigang, et al.
Publicado: (2023)

Alox12/15 Deficiency Exacerbates, While Lipoxin A(4) Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis
por: Queck, Alexander, et al.
Publicado: (2020)

Robust B Cell Responses Predict Rapid Resolution of Lyme Disease
por: Blum, Lisa K., et al.
Publicado: (2018)

12/15-Lipoxygenase Is an Interleukin-13 and Interferon-γ Counterregulated-Mediator of Allergic Airway Inflammation
por: Lindley, Alexa R., et al.
Publicado: (2010)

12/15-Lipoxygenase Regulation of Diabetic Cognitive Dysfunction Is Determined by Interfering with Inflammation and Cell Apoptosis
por: Chen, Qi, et al.
Publicado: (2022)

A Novel Function for 15-Lipoxygenases in Cholesterol Homeostasis and CCL17 Production in Human Macrophages
por: Snodgrass, Ryan G., et al.
Publicado: (2018)

15-Deoxy-Delta-12,14-Prostaglandin J(2) Inhibits Lung Inflammation and Remodeling in Distinct Murine Models of Asthma
por: Coutinho, Diego S., et al.
Publicado: (2017)

Hamster and Murine Models of Severe Destructive Lyme Arthritis
por: Munson, Erik, et al.
Publicado: (2012)

Identification of 12/15-lipoxygenase as a suppressor of myeloproliferative disease
por: Middleton, Melissa Kristine, et al.
Publicado: (2006)

A novel role for 12/15-lipoxygenase in regulating autophagy
por: Morgan, Alwena H., et al.
Publicado: (2014)

12/15-lipoxygenase inhibition attenuates neuroinflammation by suppressing inflammasomes
por: Cakir-Aktas, Canan, et al.
Publicado: (2023)

The role of eicosanoids in experimental Lyme arthritis
por: Pratt, Carmela L., et al.
Publicado: (2014)

Cathelicidin and Calprotectin Are Disparately Altered in Murine Models of Inflammatory Arthritis and Airway Inflammation
por: Hemshekhar, Mahadevappa, et al.
Publicado: (2020)

Allosteric Activation of 15‐Lipoxygenase‐1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation
por: Börner, Friedemann, et al.
Publicado: (2022)

15-Deoxy-△(12,14)-Prostaglandin J(2) Promotes Resolution of Experimentally Induced Colitis
por: Kim, Wonki, et al.
Publicado: (2021)

12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance
por: Uderhardt, Stefan, et al.
Publicado: (2011)

Soluble CD83 Triggers Resolution of Arthritis and Sustained Inflammation Control in IDO Dependent Manner
por: Royzman, Dmytro, et al.
Publicado: (2019)

12/15-Lipoxygenase Is Required for the Early Onset of High Fat Diet-Induced Adipose Tissue Inflammation and Insulin Resistance in Mice
por: Sears, Dorothy D., et al.
Publicado: (2009)

Angiotensin-(1-7) Promotes Resolution of Neutrophilic Inflammation in a Model of Antigen-Induced Arthritis in Mice
por: Barroso, Lívia C., et al.
Publicado: (2017)

Potent and Selective Inhibitors of Human Reticulocyte 12/15-Lipoxygenase as Anti-Stroke Therapies
por: Rai, Ganesha, et al.
Publicado: (2014)

Analysis of 12/15-lipoxygenase metabolism of EPA and DHA with special attention to authentication of docosatrienes
por: Jin, Jing, et al.
Publicado: (2021)

Effects of Inflammatory Factor Expression Regulated by 12/15 Lipoxygenase on Obesity-Related Nephropathy
por: Liu, Nian, et al.
Publicado: (2022)

Hematopoietic 12/15-lipoxygenase activity negatively contributes to fungal-associated allergic asthma
por: Makullah, Mgayya, et al.
Publicado: (2023)

Arachidonate 15-lipoxygenase-mediated production of Resolvin D5(n-3 DPA) abrogates pancreatic stellate cell-induced cancer cell invasion
por: Aguirre, Gabriel A., et al.
Publicado: (2023)

Sciatic–Vagal Nerve Stimulation by Electroacupuncture Alleviates Inflammatory Arthritis in Lyme Disease-Susceptible C3H Mice
por: Akoolo, Lavoisier, et al.
Publicado: (2022)

12-Lipoxygenase governs the innate immune pathogenesis of islet inflammation and autoimmune diabetes
por: Kulkarni, Abhishek, et al.
Publicado: (2021)

Emerging Role of Eosinophils in Resolution of Arthritis
por: Qin, Yi, et al.
Publicado: (2021)

The soluble CD83 protein prevents bone destruction by inhibiting the formation of osteoclasts and inducing resolution of inflammation in arthritis
por: Royzman, Dmytro, et al.
Publicado: (2022)

Iron-Dependent Trafficking of 5-Lipoxygenase and Impact on Human Macrophage Activation
por: Dufrusine, Beatrice, et al.
Publicado: (2019)

Involvement of 15-lipoxygenase in early stages of atherogenesis
Publicado: (1994)

Regulation and Functions of 15-Lipoxygenases in Human Macrophages
por: Snodgrass, Ryan G., et al.
Publicado: (2019)

Macrophages in inflammation and its resolution
por: Ariel, Amiram, et al.
Publicado: (2012)

12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma
por: Mabalirajan, Ulaganathan, et al.
Publicado: (2013)

12/15-Lipoxygenase Deficiency Impairs Neutrophil Granulopoiesis and Lung Proinflammatory Responses to Aspergillus fumigatus
por: Mackel, Joseph J., et al.
Publicado: (2020)

Resolution therapy: Harnessing efferocytic macrophages to trigger the resolution of inflammation
por: Saas, Philippe, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_abc1s6ms6clbbldp9idqvvp89n