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The mitochondrion of Plasmodium falciparum is required for cellular acetyl-CoA metabolism and protein acetylation
Coenzyme A (CoA) biosynthesis is an excellent target for antimalarial intervention. While most studies have focused on the use of CoA to produce acetyl-CoA in the apicoplast and the cytosol of malaria parasites, mitochondrial acetyl-CoA production is less well understood. In the current study, we pe...
Autores principales: | Nair, Sethu C., Munro, Justin T., Mann, Alexis, Llinás, Manuel, Prigge, Sean T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151609/ https://www.ncbi.nlm.nih.gov/pubmed/37068227 http://dx.doi.org/10.1073/pnas.2210929120 |
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