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The mitochondrion of Plasmodium falciparum is required for cellular acetyl-CoA metabolism and protein acetylation

Coenzyme A (CoA) biosynthesis is an excellent target for antimalarial intervention. While most studies have focused on the use of CoA to produce acetyl-CoA in the apicoplast and the cytosol of malaria parasites, mitochondrial acetyl-CoA production is less well understood. In the current study, we pe...

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Detalles Bibliográficos
Autores principales: Nair, Sethu C., Munro, Justin T., Mann, Alexis, Llinás, Manuel, Prigge, Sean T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151609/
https://www.ncbi.nlm.nih.gov/pubmed/37068227
http://dx.doi.org/10.1073/pnas.2210929120

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