Cargando…

Injectable Poloxamer Hydrogel Formulations for Intratympanic Delivery of Dexamethasone

BACKGROUND: In this study, we prepared and evaluated an injectable poloxamer (P407) hydrogel formulation for intratympanic (IT) delivery of dexamethasone (DEX). METHODS: DEX-loaded P407 hydrogels were characterized in terms of thermogelation, drug loading capacities, particle size, and drug release....

Descripción completa

Detalles Bibliográficos
Autores principales:	Le, Thi Phuc, Yu, Yang, Cho, Ik Sung, Suh, Eun Yeong, Kwon, Hyuk Chan, Shin, Sun-Ae, Park, Yong-Ho, Huh, Kang Moo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Academy of Medical Sciences 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151621/ https://www.ncbi.nlm.nih.gov/pubmed/37128878 http://dx.doi.org/10.3346/jkms.2023.38.e135

Ejemplares similares

Formulation of Poloxamers for Drug Delivery
por: Bodratti, Andrew M., et al.
Publicado: (2018)

Efficiency of a dexamethasone nanosuspension as an intratympanic injection for acute hearing loss
por: Jung, So-Young, et al.
Publicado: (2021)

Intratympanic dexamethasone injection for sudden sensorineural hearing loss in pregnancy
por: Lyu, Yan-Lu, et al.
Publicado: (2020)

Clinical Analysis of Intratympanic Injection of Dexamethasone for Treating Sudden Deafness
por: Li, Xin, et al.
Publicado: (2021)

In Vivo Imaging of Click-Crosslinked Hydrogel Depots Following Intratympanic Injection
por: Ju, Hyeon Jin, et al.
Publicado: (2020)

Injectable Poloxamer Hydrogels for Local Cancer Therapy
por: Marques, Ana Camila, et al.
Publicado: (2023)

Duration of symptom control following intratympanic dexamethasone injections in Meniere’s disease
por: Hilton, Aidan, et al.
Publicado: (2022)

Dual Viscosity Mixture Vehicle for Intratympanic Dexamethasone Delivery Can Block Ototoxic Hearing Loss
por: Li, Hui, et al.
Publicado: (2021)

Systemic effects of intratympanic dexamethasone therapy
por: Novoa, Eva, et al.
Publicado: (2014)

Thermosensitive Poloxamer-graft-Carboxymethyl Pullulan: A Potential Injectable Hydrogel for Drug Delivery
por: Constantin, Marieta, et al.
Publicado: (2021)

Intratympanic injection of dexamethasone for treatment of tinnitus in patients with sudden sensorineural hearing loss
por: Yoshida, Tadao, et al.
Publicado: (2012)

Intratympanic injection of hydrogel nanodrug for the prevention and treatment of sensorineural hearing loss
por: Zhai, Tianying, et al.
Publicado: (2023)

Intratympanic dexamethasone injection vs methylprednisolone for the treatment of refractory sudden sensorineural hearing loss
por: Berjis, Nezamoddin, et al.
Publicado: (2016)

Therapeutic Effect of Intratympanic Injection of Dexamethasone plus Hyaluronic Acid on Patients with Meniere's disease
por: Rogha, Mehrdad, et al.
Publicado: (2019)

Effectiveness of Intratympanic Dexamethasone Injection for Tinnitus Treatment: A Systematic Review and Meta-Analysis
por: Chung, Juyong, et al.
Publicado: (2022)

Intratympanic injection of dexamethasone for management of labyrinthitis associated with COVID-19 disease resistant cases
por: Ismaiel, Wael F., et al.
Publicado: (2022)

Drug-Loaded Biocompatible Nanocarriers Embedded in Poloxamer 407 Hydrogels as Therapeutic Formulations
por: Giuliano, Elena, et al.
Publicado: (2018)

Poloxamer Hydrogels for Biomedical Applications
por: Russo, Eleonora, et al.
Publicado: (2019)

The Effect of Intracochlear and Intratympanic Dexamethasone on Cochlear Implant Impedance
por: Ardıç, Fazıl Necdet, et al.
Publicado: (2023)

Intratympanic Dexamethasone Role in Hearing Protection in Cancer Patients
por: Gupta, Dipti, et al.
Publicado: (2023)

Intratympanic Injection of Dexamethasone and Electrocochleographic Data in Cases of Definite One Sided Refractory Meniere’s Disease
por: Dabiri Satri, Sasan, et al.
Publicado: (2017)

Assessment of complications due to intratympanic injections
por: Liu, Yu-Chuan, et al.
Publicado: (2016)

Intratympanic dexamethasone for managing pregnant women with sudden hearing loss
por: Fu, Yaoyao, et al.
Publicado: (2018)

Mucoadhesive Poloxamer-Based Hydrogels for the Release of HP-β-CD-Complexed Dexamethasone in the Treatment of Buccal Diseases
por: Diaz-Salmeron, Raul, et al.
Publicado: (2021)

Preparation of Injectable Composite Hydrogels by Blending Poloxamers with Calcium Carbonate‐Crosslinked Sodium Alginate
por: Xu, Ningxia, et al.
Publicado: (2020)

Effect of Intratympanic Dexamethasone on Controlling Tinnitus and Hearing loss in Meniere’s Disease
por: Memari, Faramarz, et al.
Publicado: (2014)

Consensus on intratympanic drug delivery for Menière’s disease
por: Li, Shuna, et al.
Publicado: (2022)

Correction: Effect of Intratympanic Dexamethasone on Controlling Tinnitus and Hearing loss in Meniere’s Disease
Publicado: (2014)

Sustained Release of Triamcinolone Acetonide from an Intratympanically Applied Hydrogel Designed for the Delivery of High Glucocorticoid Doses
por: Honeder, Clemens, et al.
Publicado: (2014)

Mucosal Applications of Poloxamer 407-Based Hydrogels: An Overview
por: Giuliano, Elena, et al.
Publicado: (2018)

Effects of an Intratympanic Injection of Dexamethasone Combined with Gentamicin on the Expression Level of Serum P0 Protein Antibodies in Patients with Meniere’s Disease
por: Geng, Yang, et al.
Publicado: (2020)

Serous otitis media: Clinical and therapeutic considerations, including dexamethasone (C(22)H(29)FO(5)) intratympanic injection
por: Mârțu, Cristian, et al.
Publicado: (2022)

Mechanical, Rheological and Release Behaviors of a Poloxamer 407/Poloxamer 188/Carbopol 940 Thermosensitive Composite Hydrogel
por: Chen, Jianping, et al.
Publicado: (2013)

Chitosan/Pluronic F127 Thermosensitive Hydrogel as an Injectable Dexamethasone Delivery Carrier
por: García-Couce, Jomarien, et al.
Publicado: (2022)

Investigation of Combined Cyclodextrin and Hydrogel Formulation for Ocular Delivery of Dexamethasone Acetate by Means of Experimental Designs
por: Mazet, Roseline, et al.
Publicado: (2018)

Quality of life after intratympanic steroid injection for Ménière's disease
por: Schenck, Annejet A., et al.
Publicado: (2022)

Rheological and Drug Delivery Characteristics of Poloxamer-Based Diclofenac Sodium Formulations for Chronic Wound Site Analgesia
por: Russo, Jackson, et al.
Publicado: (2020)

Poloxamer 407 Based Gel Formulations for Transungual Delivery of Hydrophobic Drugs: Selection and Optimization of Potential Additives
por: Ullah, Kamran Hidayat, et al.
Publicado: (2021)

Poloxamer-Based Hydrogel as Drug Delivery System: How Polymeric Excipients Influence the Chemical-Physical Properties
por: Brambilla, Elisa, et al.
Publicado: (2022)

Effectiveness of intratympanic dexamethasone for the treatment of vertigo attacks in patients with Ménière’s disease compared with betahistine pharmacotherapy
por: Molnár, András, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_p09a742odf8brelbpub24r59e6