Multidrug chemotherapy, whole-brain radiation and cytarabine therapy for primary central nervous system lymphoma in elderly patients with dose modification based on geriatric assessment: study protocol for a phase II, multicentre, non-randomised study

INTRODUCTION: Multidrug chemoimmunotherapy with rituximab, high-dose methotrexate, procarbazine and vincristine (R-MPV) is a standard therapy for younger patients with primary central nervous system lymphoma (PCNSL); however, prospective data regarding its use in elderly patients are lacking. This m...

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Detalles Bibliográficos
Autores principales: Yamasaki, Fumiyuki, Fudaba, Hirotaka, Asano, Kenichiro, Sasayama, Takashi, Natsumeda, Manabu, Shimabukuro, Taichi, Taguchi, Kotaro, Koizumi, Shinichiro, Nakayama, Noriyuki, Fujii, Kentaro, Nishibuchi, Ikuno, Sugiyama, Kazuhiko, Yoshida, Kenji, Yonezawa, Ushio, Yasutomo, Momii, Kawasaki, Yukari, Kakuta, Kiyohide, Katayama, Kosuke, Tanaka, Kazuhiro, Nagashima, Hiroaki, Tsukamoto, Yoshihiro, Ideguchi, Makoto, Nishizaki, Takafumi, Kurozumi, Kazuhiko, Hosoya, Tomohiro, Akita, Tomoyuki, Kambe, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151848/
https://www.ncbi.nlm.nih.gov/pubmed/37094899
http://dx.doi.org/10.1136/bmjopen-2022-071350

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