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Multidrug chemotherapy, whole-brain radiation and cytarabine therapy for primary central nervous system lymphoma in elderly patients with dose modification based on geriatric assessment: study protocol for a phase II, multicentre, non-randomised study
INTRODUCTION: Multidrug chemoimmunotherapy with rituximab, high-dose methotrexate, procarbazine and vincristine (R-MPV) is a standard therapy for younger patients with primary central nervous system lymphoma (PCNSL); however, prospective data regarding its use in elderly patients are lacking. This m...
Autores principales: | Yamasaki, Fumiyuki, Fudaba, Hirotaka, Asano, Kenichiro, Sasayama, Takashi, Natsumeda, Manabu, Shimabukuro, Taichi, Taguchi, Kotaro, Koizumi, Shinichiro, Nakayama, Noriyuki, Fujii, Kentaro, Nishibuchi, Ikuno, Sugiyama, Kazuhiko, Yoshida, Kenji, Yonezawa, Ushio, Yasutomo, Momii, Kawasaki, Yukari, Kakuta, Kiyohide, Katayama, Kosuke, Tanaka, Kazuhiro, Nagashima, Hiroaki, Tsukamoto, Yoshihiro, Ideguchi, Makoto, Nishizaki, Takafumi, Kurozumi, Kazuhiko, Hosoya, Tomohiro, Akita, Tomoyuki, Kambe, Atsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151848/ https://www.ncbi.nlm.nih.gov/pubmed/37094899 http://dx.doi.org/10.1136/bmjopen-2022-071350 |
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