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Geospatial characterization of immune cell distributions and dynamics across the microenvironment in clear cell renal cell carcinoma

INTRODUCTION: In clear cell renal cell carcinoma (ccRCC), tumor-associated macrophage (TAM) induction of CD8+T cells into a terminally exhausted state has been implicated as a major mechanism of immunotherapy resistance, but a deeper biological understanding is necessary. METHODS: Primary ccRCC tumo...

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Detalles Bibliográficos
Autores principales:	Chakiryan, Nicholas H, Kim, Youngchul, Berglund, Anders, Chang, Andrew, Kimmel, Gregory J, Hajiran, Ali, Nguyen, Jonathan, Moran-Segura, Carlos, Saeed-Vafa, Daryoush, Katende, Esther N, Lopez-Blanco, Neale, Chahoud, Jad, Rappold, Phillip, Spiess, Philippe E, Fournier, Michelle, Jeong, Daniel, Wang, Liang, Teer, Jamie K, Dhillon, Jasreman, Kuo, Fengshen, Hakimi, Abraham Ari, Altrock, Philipp M, Mulé, James J, Manley, Brandon J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Clinical/Translational Cancer Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151991/ https://www.ncbi.nlm.nih.gov/pubmed/37185232 http://dx.doi.org/10.1136/jitc-2022-006195

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