Vector Aided Microenvironment programming (VAMP): reprogramming the TME with MVA virus expressing IL-12 for effective antitumor activity

BACKGROUND: Tumor microenvironment (TME) represents a critical hurdle in cancer immunotherapy, given its ability to suppress antitumor immunity. Several efforts are made to overcome this hostile TME with the development of new therapeutic strategies modifying TME to boost antitumor immunity. Among t...

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Detalles Bibliográficos
Autores principales: Seclì, Laura, Infante, Luigia, Nocchi, Linda, De Lucia, Maria, Cotugno, Gabriella, Leoni, Guido, Micarelli, Elisa, Garzia, Irene, Avalle, Lidia, Sdruscia, Giulia, Troise, Fulvia, Allocca, Simona, Romano, Giuseppina, Scarselli, Elisa, D'Alise, Anna Morena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151998/
https://www.ncbi.nlm.nih.gov/pubmed/37117006
http://dx.doi.org/10.1136/jitc-2023-006718

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