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Risk factors and interventions for developing recurrent pneumonia in older adults

BACKGROUND: Pneumonia is common among older adults and often recurrent. Several studies have been conducted on the risk factors for pneumonia; however, little is known about the risk factors for recurrent pneumonia. This study aimed to identify the risk factors for developing recurrent pneumonia amo...

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Autores principales: Takada, Kazufumi, Ogawa, Kazumasa, Miyamoto, Atsushi, Nakahama, Hiroshi, Moriguchi, Shuhei, Murase, Kyoko, Hanada, Shigeo, Takaya, Hisashi, Tamaoka, Meiyo, Takai, Daiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152262/
https://www.ncbi.nlm.nih.gov/pubmed/37143835
http://dx.doi.org/10.1183/23120541.00516-2022
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author Takada, Kazufumi
Ogawa, Kazumasa
Miyamoto, Atsushi
Nakahama, Hiroshi
Moriguchi, Shuhei
Murase, Kyoko
Hanada, Shigeo
Takaya, Hisashi
Tamaoka, Meiyo
Takai, Daiya
author_facet Takada, Kazufumi
Ogawa, Kazumasa
Miyamoto, Atsushi
Nakahama, Hiroshi
Moriguchi, Shuhei
Murase, Kyoko
Hanada, Shigeo
Takaya, Hisashi
Tamaoka, Meiyo
Takai, Daiya
author_sort Takada, Kazufumi
collection PubMed
description BACKGROUND: Pneumonia is common among older adults and often recurrent. Several studies have been conducted on the risk factors for pneumonia; however, little is known about the risk factors for recurrent pneumonia. This study aimed to identify the risk factors for developing recurrent pneumonia among older adults and to investigate methods of prevention. METHODS: We analysed the data of 256 patients aged 75 years or older who were admitted for pneumonia between June 2014 and May 2017. Moreover, we reviewed the medical records for the subsequent 3 years and defined the readmission caused by pneumonia as recurrent pneumonia. Risk factors for recurrent pneumonia were analysed using multivariable logistic regression analysis. Differences in the recurrence rate based on the types and use of hypnotics were also evaluated. RESULTS: Of the 256 patients, 90 (35.2%) experienced recurrent pneumonia. A low body mass index (OR: 0.91; 95% CI: 0.83‒0.99), history of pneumonia (OR: 2.71; 95% CI: 1.23‒6.13), lung disease as a comorbidity (OR: 4.73; 95% CI: 2.13‒11.60), taking hypnotics (OR: 2.16; 95% CI: 1.18‒4.01) and taking histamine-1 receptor antagonist (H1RA) (OR: 2.38; 95% CI: 1.07‒5.39) were risk factors. Patients taking benzodiazepine as hypnotics were more likely to experience recurrent pneumonia than patients not taking hypnotics (OR: 2.29; 95% CI: 1.25–4.18). CONCLUSION: We identified several risk factors for recurrent pneumonia. Among them, restricting the use of H1RA and hypnotics, in particular benzodiazepines, may be useful in preventing the recurrence of pneumonia in adults aged 75 years or older.
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spelling pubmed-101522622023-05-03 Risk factors and interventions for developing recurrent pneumonia in older adults Takada, Kazufumi Ogawa, Kazumasa Miyamoto, Atsushi Nakahama, Hiroshi Moriguchi, Shuhei Murase, Kyoko Hanada, Shigeo Takaya, Hisashi Tamaoka, Meiyo Takai, Daiya ERJ Open Res Original Research Articles BACKGROUND: Pneumonia is common among older adults and often recurrent. Several studies have been conducted on the risk factors for pneumonia; however, little is known about the risk factors for recurrent pneumonia. This study aimed to identify the risk factors for developing recurrent pneumonia among older adults and to investigate methods of prevention. METHODS: We analysed the data of 256 patients aged 75 years or older who were admitted for pneumonia between June 2014 and May 2017. Moreover, we reviewed the medical records for the subsequent 3 years and defined the readmission caused by pneumonia as recurrent pneumonia. Risk factors for recurrent pneumonia were analysed using multivariable logistic regression analysis. Differences in the recurrence rate based on the types and use of hypnotics were also evaluated. RESULTS: Of the 256 patients, 90 (35.2%) experienced recurrent pneumonia. A low body mass index (OR: 0.91; 95% CI: 0.83‒0.99), history of pneumonia (OR: 2.71; 95% CI: 1.23‒6.13), lung disease as a comorbidity (OR: 4.73; 95% CI: 2.13‒11.60), taking hypnotics (OR: 2.16; 95% CI: 1.18‒4.01) and taking histamine-1 receptor antagonist (H1RA) (OR: 2.38; 95% CI: 1.07‒5.39) were risk factors. Patients taking benzodiazepine as hypnotics were more likely to experience recurrent pneumonia than patients not taking hypnotics (OR: 2.29; 95% CI: 1.25–4.18). CONCLUSION: We identified several risk factors for recurrent pneumonia. Among them, restricting the use of H1RA and hypnotics, in particular benzodiazepines, may be useful in preventing the recurrence of pneumonia in adults aged 75 years or older. European Respiratory Society 2023-05-02 /pmc/articles/PMC10152262/ /pubmed/37143835 http://dx.doi.org/10.1183/23120541.00516-2022 Text en Copyright ©The authors 2023 https://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org (mailto:permissions@ersnet.org)
spellingShingle Original Research Articles
Takada, Kazufumi
Ogawa, Kazumasa
Miyamoto, Atsushi
Nakahama, Hiroshi
Moriguchi, Shuhei
Murase, Kyoko
Hanada, Shigeo
Takaya, Hisashi
Tamaoka, Meiyo
Takai, Daiya
Risk factors and interventions for developing recurrent pneumonia in older adults
title Risk factors and interventions for developing recurrent pneumonia in older adults
title_full Risk factors and interventions for developing recurrent pneumonia in older adults
title_fullStr Risk factors and interventions for developing recurrent pneumonia in older adults
title_full_unstemmed Risk factors and interventions for developing recurrent pneumonia in older adults
title_short Risk factors and interventions for developing recurrent pneumonia in older adults
title_sort risk factors and interventions for developing recurrent pneumonia in older adults
topic Original Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152262/
https://www.ncbi.nlm.nih.gov/pubmed/37143835
http://dx.doi.org/10.1183/23120541.00516-2022
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