SLE stratification based on BAFF and IFN-I bioactivity for biologics and implications of BAFF produced by glomeruli in lupus nephritis

OBJECTIVE: B-cell activating factor (BAFF) is implicated in SLE pathogenesis. Blocking BAFF signalling has contributed to reducing glucocorticoid dosage and preventing organ damage. However, clinical characteristics of patients who may benefit from this therapy are not yet fully elucidated. Therefor...

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Detalles Bibliográficos
Autores principales: Itotagawa, Eri, Tomofuji, Yoshihiko, Kato, Yasuhiro, Konaka, Hachiro, Tsujimoto, Kohei, Park, JeongHoon, Nagira, Daiki, Hirayama, Takehiro, Jo, Tatsunori, Hirano, Toru, Morita, Takayoshi, Nishide, Masayuki, Nishida, Sumiyuki, Shima, Yoshihito, Narazaki, Masashi, Okada, Yukinori, Takamatsu, Hyota, Kumanogoh, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152287/
https://www.ncbi.nlm.nih.gov/pubmed/36094336
http://dx.doi.org/10.1093/rheumatology/keac528

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