Cargando…
An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective
The SARS-CoV-2 pandemic has highlighted the importance of viable infection surveillance and the relevant infrastructure. From a German perspective, an integral part of this infrastructure, genomic pathogen sequencing, was at best fragmentary and stretched to its limits due to the lack or inefficient...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152431/ https://www.ncbi.nlm.nih.gov/pubmed/37129842 http://dx.doi.org/10.1007/s15010-023-02040-9 |
_version_ | 1785035750345015296 |
---|---|
author | Salzberger, Bernd Mellmann, Alexander Bludau, Anna Ciesek, Sandra Corman, Victor Dilthey, Alexander Donker, Tjibbe Eckmanns, Tim Egelkamp, Richard Gatermann, Sören G. Grundmann, Hajo Häcker, Georg Kaase, Martin Lange, Berit Mielke, Martin Pletz, Mathias W. Semmler, Torsten Thürmer, Andrea Wieler, Lothar H. Wolff, Thorsten Widmer, Andreas F. Scheithauer, Simone |
author_facet | Salzberger, Bernd Mellmann, Alexander Bludau, Anna Ciesek, Sandra Corman, Victor Dilthey, Alexander Donker, Tjibbe Eckmanns, Tim Egelkamp, Richard Gatermann, Sören G. Grundmann, Hajo Häcker, Georg Kaase, Martin Lange, Berit Mielke, Martin Pletz, Mathias W. Semmler, Torsten Thürmer, Andrea Wieler, Lothar H. Wolff, Thorsten Widmer, Andreas F. Scheithauer, Simone |
author_sort | Salzberger, Bernd |
collection | PubMed |
description | The SARS-CoV-2 pandemic has highlighted the importance of viable infection surveillance and the relevant infrastructure. From a German perspective, an integral part of this infrastructure, genomic pathogen sequencing, was at best fragmentary and stretched to its limits due to the lack or inefficient use of equipment, human resources, data management and coordination. The experience in other countries has shown that the rate of sequenced positive samples and linkage of genomic and epidemiological data (person, place, time) represent important factors for a successful application of genomic pathogen surveillance. Planning, establishing and consistently supporting adequate structures for genomic pathogen surveillance will be crucial to identify and combat future pandemics as well as other challenges in infectious diseases such as multi-drug resistant bacteria and healthcare-associated infections. Therefore, the authors propose a multifaceted and coordinated process for the definition of procedural, legal and technical standards for comprehensive genomic pathogen surveillance in Germany, covering the areas of genomic sequencing, data collection and data linkage, as well as target pathogens. A comparative analysis of the structures established in Germany and in other countries is applied. This proposal aims to better tackle epi- and pandemics to come and take action from the “lessons learned” from the SARS-CoV-2 pandemic. |
format | Online Article Text |
id | pubmed-10152431 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-101524312023-05-03 An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective Salzberger, Bernd Mellmann, Alexander Bludau, Anna Ciesek, Sandra Corman, Victor Dilthey, Alexander Donker, Tjibbe Eckmanns, Tim Egelkamp, Richard Gatermann, Sören G. Grundmann, Hajo Häcker, Georg Kaase, Martin Lange, Berit Mielke, Martin Pletz, Mathias W. Semmler, Torsten Thürmer, Andrea Wieler, Lothar H. Wolff, Thorsten Widmer, Andreas F. Scheithauer, Simone Infection Position Statement The SARS-CoV-2 pandemic has highlighted the importance of viable infection surveillance and the relevant infrastructure. From a German perspective, an integral part of this infrastructure, genomic pathogen sequencing, was at best fragmentary and stretched to its limits due to the lack or inefficient use of equipment, human resources, data management and coordination. The experience in other countries has shown that the rate of sequenced positive samples and linkage of genomic and epidemiological data (person, place, time) represent important factors for a successful application of genomic pathogen surveillance. Planning, establishing and consistently supporting adequate structures for genomic pathogen surveillance will be crucial to identify and combat future pandemics as well as other challenges in infectious diseases such as multi-drug resistant bacteria and healthcare-associated infections. Therefore, the authors propose a multifaceted and coordinated process for the definition of procedural, legal and technical standards for comprehensive genomic pathogen surveillance in Germany, covering the areas of genomic sequencing, data collection and data linkage, as well as target pathogens. A comparative analysis of the structures established in Germany and in other countries is applied. This proposal aims to better tackle epi- and pandemics to come and take action from the “lessons learned” from the SARS-CoV-2 pandemic. Springer Berlin Heidelberg 2023-05-02 2023 /pmc/articles/PMC10152431/ /pubmed/37129842 http://dx.doi.org/10.1007/s15010-023-02040-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Position Statement Salzberger, Bernd Mellmann, Alexander Bludau, Anna Ciesek, Sandra Corman, Victor Dilthey, Alexander Donker, Tjibbe Eckmanns, Tim Egelkamp, Richard Gatermann, Sören G. Grundmann, Hajo Häcker, Georg Kaase, Martin Lange, Berit Mielke, Martin Pletz, Mathias W. Semmler, Torsten Thürmer, Andrea Wieler, Lothar H. Wolff, Thorsten Widmer, Andreas F. Scheithauer, Simone An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective |
title | An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective |
title_full | An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective |
title_fullStr | An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective |
title_full_unstemmed | An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective |
title_short | An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective |
title_sort | appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the german perspective |
topic | Position Statement |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152431/ https://www.ncbi.nlm.nih.gov/pubmed/37129842 http://dx.doi.org/10.1007/s15010-023-02040-9 |
work_keys_str_mv | AT salzbergerbernd anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT mellmannalexander anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT bludauanna anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT cieseksandra anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT cormanvictor anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT diltheyalexander anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT donkertjibbe anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT eckmannstim anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT egelkamprichard anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT gatermannsoreng anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT grundmannhajo anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT hackergeorg anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT kaasemartin anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT langeberit anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT mielkemartin anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT pletzmathiasw anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT semmlertorsten anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT thurmerandrea anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT wielerlotharh anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT wolffthorsten anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT widmerandreasf anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT scheithauersimone anappealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT salzbergerbernd appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT mellmannalexander appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT bludauanna appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT cieseksandra appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT cormanvictor appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT diltheyalexander appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT donkertjibbe appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT eckmannstim appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT egelkamprichard appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT gatermannsoreng appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT grundmannhajo appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT hackergeorg appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT kaasemartin appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT langeberit appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT mielkemartin appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT pletzmathiasw appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT semmlertorsten appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT thurmerandrea appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT wielerlotharh appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT wolffthorsten appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT widmerandreasf appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective AT scheithauersimone appealforstrengtheninggenomicpathogensurveillancetoimprovepandemicpreparednessandinfectionpreventionthegermanperspective |