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From Translation to Treatment

Protein synthesis (mRNA translation) plays a crucial role in cell function by shaping the proteome –making all the proteins each cell requires at the right time and in the right quantities and places. Proteins carry out almost every job in the cell. Protein synthesis is also a major component of the...

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Detalles Bibliográficos
Autores principales: Wang, Xuemin, Proud, Christopher G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty Opinions Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152553/
https://www.ncbi.nlm.nih.gov/pubmed/37143925
http://dx.doi.org/10.12703/r/12-9
Descripción
Sumario:Protein synthesis (mRNA translation) plays a crucial role in cell function by shaping the proteome –making all the proteins each cell requires at the right time and in the right quantities and places. Proteins carry out almost every job in the cell. Protein synthesis is also a major component of the cellular economy, using large amounts of metabolic energy and resources, especially amino acids. Accordingly, it is tightly regulated through diverse mechanisms which respond, for example, to nutrients, growth factors, hormones, neurotransmitters and stressful situations.