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Drug interference with biochemical laboratory tests

Clinical laboratory practice represents an essential part of clinical decision-making, as it influences 60-70% of medical decisions at all levels of health care. Results of biochemical laboratory tests (BLTs) have a key role in establishment of adequate diagnosis as well as in evaluation of treatmen...

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Autores principales: Katanić, Jasmina, Stanimirov, Bojan, Sekeruš, Vanesa, Đanić, Maja, Pavlović, Nebojša, Mikov, Momir, Stankov, Karmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Society of Medical Biochemistry and Laboratory Medicine 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152617/
https://www.ncbi.nlm.nih.gov/pubmed/37143715
http://dx.doi.org/10.11613/BM.2023.020601
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author Katanić, Jasmina
Stanimirov, Bojan
Sekeruš, Vanesa
Đanić, Maja
Pavlović, Nebojša
Mikov, Momir
Stankov, Karmen
author_facet Katanić, Jasmina
Stanimirov, Bojan
Sekeruš, Vanesa
Đanić, Maja
Pavlović, Nebojša
Mikov, Momir
Stankov, Karmen
author_sort Katanić, Jasmina
collection PubMed
description Clinical laboratory practice represents an essential part of clinical decision-making, as it influences 60-70% of medical decisions at all levels of health care. Results of biochemical laboratory tests (BLTs) have a key role in establishment of adequate diagnosis as well as in evaluation of treatment progress and outcome. The prevalence of drug-laboratory test interactions (DLTIs) is up to 43% of patients who had laboratory results influenced by drugs. Unrecognized DLTIs may lead to misinterpreted BLTs results, incorrect or delayed diagnosis, extra costs for unnecessary additional tests or inadequate therapy, as all may cause false clinical decisions. The significance of timely and adequate recognition of DLTIs is to prevent common clinical consequences such as incorrectly interpreted test results, delayed or non-treated condition due to erroneous diagnosis or unnecessary extra tests or therapy. Medical professionals should be educated that it is essential to obtain patient data about medications especially for the drugs used in the last 10 days before biological material collection. Our mini-review aims to provide a comprehensive overview of the current state in this important domain of medical biochemistry with detailed analysis of the effect of drugs on BLTs and to give detailed information to medical specialists.
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spelling pubmed-101526172023-05-03 Drug interference with biochemical laboratory tests Katanić, Jasmina Stanimirov, Bojan Sekeruš, Vanesa Đanić, Maja Pavlović, Nebojša Mikov, Momir Stankov, Karmen Biochem Med (Zagreb) Short Review Clinical laboratory practice represents an essential part of clinical decision-making, as it influences 60-70% of medical decisions at all levels of health care. Results of biochemical laboratory tests (BLTs) have a key role in establishment of adequate diagnosis as well as in evaluation of treatment progress and outcome. The prevalence of drug-laboratory test interactions (DLTIs) is up to 43% of patients who had laboratory results influenced by drugs. Unrecognized DLTIs may lead to misinterpreted BLTs results, incorrect or delayed diagnosis, extra costs for unnecessary additional tests or inadequate therapy, as all may cause false clinical decisions. The significance of timely and adequate recognition of DLTIs is to prevent common clinical consequences such as incorrectly interpreted test results, delayed or non-treated condition due to erroneous diagnosis or unnecessary extra tests or therapy. Medical professionals should be educated that it is essential to obtain patient data about medications especially for the drugs used in the last 10 days before biological material collection. Our mini-review aims to provide a comprehensive overview of the current state in this important domain of medical biochemistry with detailed analysis of the effect of drugs on BLTs and to give detailed information to medical specialists. Croatian Society of Medical Biochemistry and Laboratory Medicine 2023-04-15 2023-06-15 /pmc/articles/PMC10152617/ /pubmed/37143715 http://dx.doi.org/10.11613/BM.2023.020601 Text en Croatian Society of Medical Biochemistry and Laboratory Medicine. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Review
Katanić, Jasmina
Stanimirov, Bojan
Sekeruš, Vanesa
Đanić, Maja
Pavlović, Nebojša
Mikov, Momir
Stankov, Karmen
Drug interference with biochemical laboratory tests
title Drug interference with biochemical laboratory tests
title_full Drug interference with biochemical laboratory tests
title_fullStr Drug interference with biochemical laboratory tests
title_full_unstemmed Drug interference with biochemical laboratory tests
title_short Drug interference with biochemical laboratory tests
title_sort drug interference with biochemical laboratory tests
topic Short Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152617/
https://www.ncbi.nlm.nih.gov/pubmed/37143715
http://dx.doi.org/10.11613/BM.2023.020601
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