SARS-CoV-2 Omicron subvariant spike N405 unlikely to rapidly deamidate

The RGD motif on the SARS-CoV-2 spike protein has been suggested to interact with RGD-binding integrins αVβ3 and α5β1 to enhance viral cell entry and alter downstream signaling cascades. The D405N mutation on the Omicron subvariant spike proteins, resulting in an RGN motif, has recently been shown t...

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Detalles Bibliográficos
Autores principales: Beaudoin, Christopher A., Petsolari, Emmanouela, Hamaia, Samir W., Hala, Sharif, Alofi, Fadwa S., Pandurangan, Arun P., Blundell, Tom L., Chaitanya Vedithi, Sundeep, Huang, Christopher L.-H., Jackson, Antony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152834/
https://www.ncbi.nlm.nih.gov/pubmed/37178506
http://dx.doi.org/10.1016/j.bbrc.2023.04.088

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