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Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy
OBJECTIVE: A study on dosimetric characteristics of silicon elastomer-based bolus was carried out using a Linear accelerator (Varian – Unique Performance). The study is performed to know if the silicone elastomer based bolus can be used in the radiotherapy. A bolus is a tissue equivalent material us...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
West Asia Organization for Cancer Prevention
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152843/ https://www.ncbi.nlm.nih.gov/pubmed/36708562 http://dx.doi.org/10.31557/APJCP.2023.24.1.141 |
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author | Boopathi, M Khanna, D Venkatraman, P Varshini, R Sureka, C S Pooja, S |
author_facet | Boopathi, M Khanna, D Venkatraman, P Varshini, R Sureka, C S Pooja, S |
author_sort | Boopathi, M |
collection | PubMed |
description | OBJECTIVE: A study on dosimetric characteristics of silicon elastomer-based bolus was carried out using a Linear accelerator (Varian – Unique Performance). The study is performed to know if the silicone elastomer based bolus can be used in the radiotherapy. A bolus is a tissue equivalent material used to provide uniform dose to the uneven surface contours. It is exposed during the radiation therapy and also provides maximum dose (dmax) to treat surface tumors in case of high energy photons like megavoltage therapy photons. It is used in the case of external beam radiation therapy. METHODS: In this study, the bolus was fabricated using PDMS substrate with a curing agent by the ratio of 10:1. The bolus was fabricated in two thicknesses 0.5cm and 1cm. The dosimetric characteristics like transmission factor, mass attenuation coefficient, durability, homogeneity, density test of the fabricated bolus were studied. RESULTS: The dosimetric characteristics of the silicone elastomer based bolus were studied over a period of one month by exposing it in a 6MV photon. The result of the study shows that the silicone elastomer based bolus fabricated, satisfies the dosimetric characteristics needed for a tissue equivalent bolus to be used in the radiation therapy. CONCLUSIONS: The fabricated bolus could increase the percentage surface dose, reduce skin-sparing effect, and protect OAR. The aim of this is to provide an adjustable, transparent, and easily fabricated, less expensive, nontoxic bolus which can be used in the radiotherapy. |
format | Online Article Text |
id | pubmed-10152843 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | West Asia Organization for Cancer Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-101528432023-05-03 Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy Boopathi, M Khanna, D Venkatraman, P Varshini, R Sureka, C S Pooja, S Asian Pac J Cancer Prev Research Article OBJECTIVE: A study on dosimetric characteristics of silicon elastomer-based bolus was carried out using a Linear accelerator (Varian – Unique Performance). The study is performed to know if the silicone elastomer based bolus can be used in the radiotherapy. A bolus is a tissue equivalent material used to provide uniform dose to the uneven surface contours. It is exposed during the radiation therapy and also provides maximum dose (dmax) to treat surface tumors in case of high energy photons like megavoltage therapy photons. It is used in the case of external beam radiation therapy. METHODS: In this study, the bolus was fabricated using PDMS substrate with a curing agent by the ratio of 10:1. The bolus was fabricated in two thicknesses 0.5cm and 1cm. The dosimetric characteristics like transmission factor, mass attenuation coefficient, durability, homogeneity, density test of the fabricated bolus were studied. RESULTS: The dosimetric characteristics of the silicone elastomer based bolus were studied over a period of one month by exposing it in a 6MV photon. The result of the study shows that the silicone elastomer based bolus fabricated, satisfies the dosimetric characteristics needed for a tissue equivalent bolus to be used in the radiation therapy. CONCLUSIONS: The fabricated bolus could increase the percentage surface dose, reduce skin-sparing effect, and protect OAR. The aim of this is to provide an adjustable, transparent, and easily fabricated, less expensive, nontoxic bolus which can be used in the radiotherapy. West Asia Organization for Cancer Prevention 2023 /pmc/articles/PMC10152843/ /pubmed/36708562 http://dx.doi.org/10.31557/APJCP.2023.24.1.141 Text en https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License.https://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Research Article Boopathi, M Khanna, D Venkatraman, P Varshini, R Sureka, C S Pooja, S Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy |
title | Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy |
title_full | Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy |
title_fullStr | Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy |
title_full_unstemmed | Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy |
title_short | Fabrication and Dosimetric Characteristics of Silicon Elastomer-Based Bolus Using External Beam Radiotherapy |
title_sort | fabrication and dosimetric characteristics of silicon elastomer-based bolus using external beam radiotherapy |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152843/ https://www.ncbi.nlm.nih.gov/pubmed/36708562 http://dx.doi.org/10.31557/APJCP.2023.24.1.141 |
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