PTEN knockout using retrogradely transported AAVs restores locomotor abilities in both acute and chronic spinal cord injury

Restoring function in chronic stages of spinal cord injury (SCI) has often been met with failure or reduced efficacy when regenerative strategies are delayed past the acute or sub-acute stages of injury. Restoring function in the chronically injured spinal cord remains a critical challenge. We found...

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Detalles Bibliográficos
Autores principales: Stewart, Andrew N., Kumari, Reena, Bailey, William M., Glaser, Ethan P., Hammers, Gabrielle V., Wireman, Olivia H., Gensel, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153160/
https://www.ncbi.nlm.nih.gov/pubmed/37131840
http://dx.doi.org/10.1101/2023.04.17.537179

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