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Computational design of non-porous, pH-responsive antibody nanoparticles

Programming protein nanomaterials to respond to changes in environmental conditions is a current challenge for protein design and important for targeted delivery of biologics. We describe the design of octahedral non-porous nanoparticles with the three symmetry axes (four-fold, three-fold, and two-f...

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Detalles Bibliográficos
Autores principales: Yang, Erin C., Divine, Robby, Miranda, Marcos C., Borst, Andrew J., Sheffler, Will, Zhang, Jason Z, Decarreau, Justin, Saragovi, Amijai, Abedi, Mohamad, Goldbach, Nicolas, Ahlrichs, Maggie, Dobbins, Craig, Hand, Alexis, Cheng, Suna, Lamb, Mila, Levine, Paul M., Chan, Sidney, Skotheim, Rebecca, Fallas, Jorge, Ueda, George, Lubner, Joshua, Somiya, Masaharu, Khmelinskaia, Alena, King, Neil P., Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153164/
https://www.ncbi.nlm.nih.gov/pubmed/37131615
http://dx.doi.org/10.1101/2023.04.17.537263