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Imaging-based screening identifies modulators of the eIF3 translation initiation factor complex in Candida albicans
Fungal pathogens like Candida albicans can cause devastating human disease. Treatment of candidemia is complicated by the high rate of resistance to common antifungal therapies. Additionally, there is host toxicity associated with many antifungal compounds due to the conservation between essential m...
Autores principales: | Metzner, Katura, O’Meara, Matthew J, Halligan, Benjamin, Wotring, Jesse W., Sexton, Jonathan Z, O’Meara, Teresa R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153179/ https://www.ncbi.nlm.nih.gov/pubmed/37131825 http://dx.doi.org/10.1101/2023.04.19.537517 |
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