Intermediate antiparallel beta structure in amyloid plaques revealed by infrared spectroscopic imaging

Aggregation of amyloid beta (Aβ) peptides into extracellular plaques is a hallmark of the molecular pathology of Alzheimer’s disease (AD). Amyloid aggregates have been extensively studied in-vitro, and it is well known that mature amyloid fibrils contain an ordered parallel β structure. The structur...

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Detalles Bibliográficos
Autores principales: Holcombe, Brooke, Foes, Abigail, Banerjee, Siddhartha, Yeh, Kevin, Wang, Shih-Hsiu J., Bhargava, Rohit, Ghosh, Ayanjeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153194/
https://www.ncbi.nlm.nih.gov/pubmed/37131832
http://dx.doi.org/10.1101/2023.04.18.537414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153194/
https://www.ncbi.nlm.nih.gov/pubmed/37131832
http://dx.doi.org/10.1101/2023.04.18.537414

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