Human cytomegalovirus attenuates AKT activity by destabilizing insulin receptor substrate proteins

The phosphoinositide 3-kinase (PI3K)/AKT pathway plays crucial roles in cell viability and protein synthesis and is frequently co-opted by viruses to support their replication. Although many viruses maintain high levels of AKT activity during infection, other viruses, such as vesicular stomatitis vi...

Descripción completa

Detalles Bibliográficos
Autores principales: Domma, Anthony J., Goodrum, Felicia D., Moorman, Nathaniel J., Kamil, Jeremy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153195/
https://www.ncbi.nlm.nih.gov/pubmed/37131605
http://dx.doi.org/10.1101/2023.04.17.537203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153195/
https://www.ncbi.nlm.nih.gov/pubmed/37131605
http://dx.doi.org/10.1101/2023.04.17.537203

Ejemplares similares