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Gene regulatory network inference with popInfer reveals dynamic regulation of hematopoietic stem cell quiescence upon diet restriction and aging

Inference of gene regulatory networks (GRNs) can reveal cell state transitions from single-cell genomics data. However, obstacles to temporal inference from snapshot data are difficult to overcome. Single-nuclei multiomics data offer means to bridge this gap and derive temporal information from snap...

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Detalles Bibliográficos
Autores principales:	Rommelfanger, Megan K., Behrends, Marthe, Chen, Yulin, Martinez, Jonathan, Bens, Martin, Xiong, Lingyun, Rudolph, K. Lenhard, MacLean, Adam L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153203/ https://www.ncbi.nlm.nih.gov/pubmed/37131596 http://dx.doi.org/10.1101/2023.04.18.537360

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