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LonP1 Drives Proneural Mesenchymal Transition in IDH1-R132H Diffuse Glioma

Malignant astroctyoma and glioblastoma are diffuse CNS tumors that have markedly similar features, including microvascular proliferation and necrosis, and the latter presents higher grade and poorer survival. The Isocitrate dehydrogenase 1/2 (IDH) mutation further predicts improved survival and is p...

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Detalles Bibliográficos
Autores principales: Douglas, Christopher, Lomeli, Naomi, Vu, Thao, Pham, James, Bota, Daniela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153221/
https://www.ncbi.nlm.nih.gov/pubmed/37131765
http://dx.doi.org/10.1101/2023.04.13.536817