Fibertools: fast and accurate DNA-m6A calling using single-molecule long-read sequencing

Single-molecule chromatin fiber sequencing is based on the single-nucleotide resolution identification of DNA N(6)-methyladenine (m6A) along individual sequencing reads. We present fibertools, a semi-supervised convolutional neural network that permits the fast and accurate identification of both en...

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Detalles Bibliográficos
Autores principales: Jha, Anupama, Bohaczuk, Stephanie C., Mao, Yizi, Ranchalis, Jane, Mallory, Benjamin J., Min, Alan T., Hamm, Morgan O., Swanson, Elliott, Finkbeiner, Connor, Li, Tony, Whittington, Dale, Noble, William Stafford, Stergachis, Andrew B., Vollger, Mitchell R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153250/
https://www.ncbi.nlm.nih.gov/pubmed/37131601
http://dx.doi.org/10.1101/2023.04.20.537673

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